Abstract
The aim of this study was to evaluate the effect of prescribing vitamin D on improving
the symptoms of patients diagnosed with urosepsis. The participants were randomly
divided into two equal groups (each consisting of 50 patients). The patients in the
first group received standard treatment with 300 000 units of injected vitamin with
a volume of 1 cc. As for the patients in the second group, they received standard
treatment along with 1 cc normal saline injected to them as placebo. Vital signs of
the patients were checked every 6 h, while their CBC, EXR, CRP, creatinine, urea,
and uric acid were checked 0, 24, 48, and 72 h following the interventions. Calcium,
phosphorus, and vitamin D levels were measured 72 h following injection of the medicine.
A significant difference was observed between the two groups in terms of the number
of WBC’s in 24th, 48th, and 72nd hours. A similarly significant difference was reported
between the case and control group in terms of the average BUN within 24th, 48th,
and 72nd hours. The difference observed between the two groups in terms of average
Cr within the 0th, 24th, 48th, and 72nd hours and in terms of days of hospitalization
was also significant. Considering these results and keeping in mind the fact that
no particular side effects were reported as a result of utilizing muscular injections
of vitamin D and the easy and cheap use of this medicine, it can be used in auxiliary
treatment of patients with urosepsis.
Key words
vitamin D - prognosis - urosepsis - patients
